Simple mathematical models on macrophages and CTL responses against Mycobacterium tuberculosis

  • Eduardo Ibargüen-Mondragón
  • Lourdes Esteva
Palabras clave: Modelo matemático, Tuberculosis, Estabilidad, Inmunología, soluciones de equilibrio, Mathematical model, Stability, Immunology, Equilibrium solutions.



En este trabajo se formulan cuatro modelos matemáticos que intentan describir aspectos básicos de la dinámica de la infección con el Micobacterium tuberculosis (Mtb) en diferentes etapas.
El propósito de este estudio es evaluar el impacto de la respuesta de las células T y los macrófagos en el control del Mtb.



In this work we formulate fourth mathematical models trying to describe basic aspects
into the dynamics of theMycobacterium tuberculosis (Mtb) infection at different stages. The purpose
of this study is to evaluate the impact of the response of T cells and macrophages in the control of


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Biografía del autor/a

Eduardo Ibargüen-Mondragón

Departamento de Matemáticas y Estadística, Facultad de Ciencias Exactas y
Naturales, Universidad de Nariño, C. U. Torobajo, Clle 18 - Cra 50, PBX 27311449, Pasto, Colombia.

Lourdes Esteva

Departamento deMatemáticas, Facultad de Ciencias, Universidad Nacional Autónoma de México, 04510,
México, DF.


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