The main aim of this article is to rebuild the historical journey that Mettler House has developed over the years since its origin based on Swiss and Colombian heritage. The beginning of this enterprise´s commercial activities match with the time Nariño has existed as a Colombian department. Settled in this region of southern Colombia, it has remained until present days. The perseverance regarding its spirit of service, within conditions of one of the less developed areas of Colombia, has been a key factor for achieving a positive social and economic integration. Today Mettler House is part of the regional business’s heritage.