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Social determinants of health

Vol. 28 No. Suppl 1 (2026): Special issue: H. pylori and Gastric Cancer in the Americas

A holistic and dynamic view of gastric carcinogenesis

DOI
https://doi.org/10.22267/rus.2628s1.10135
Submitted
March 18, 2026
Published
2026-10-05

Abstract

Introduction: Gastric carcinogenesis is a multifactorial process that leads to gastric cancer (GC). Currently, the components that influence the intricate interactions in the precancerous cascade, comprising the host, environmental factors, and the agent (Helicobacter pylori), are variable. Likewise, current evidence has enabled us to gain a more holistic understanding of each factor's performance and its role in gastric carcinogenesis within the Correa model.

Objective: To explore the most recent scientific advances in the conceptual field.

Conclusion: A model is proposed based on recent research on gastric carcinogenesis conducted in Colombian populations in recent years.

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