Miocardiocitos conducentes ventriculares

  • Doris Haydee Rosero Salazar Universidad del Valle
  • Mario Alejandro Ortiz Salazar Universidad del Valle
  • Liliana Salazar Monsalve Universidad del Valle
Palabras clave: Palabras clave, Miocardiocitos conducentes ventriculares, miocardio, arritmia cardiaca, ventrículo cardiaco, Leading ventricular cardiomyocytes, myocardium, cardiac arrhythmia, cardiac ventricle

Resumen

 

 Resumen

Objetivo: Exponer las características histológicas y funcionales que se presentan en el tejido muscular estriado cardíaco especializado en la conducción del estímulo eléctrico y sus implicaciones actuales en las arritmias cardíacas. Materiales y métodos: Se seleccionaron publicaciones en revistas indexadas en las bases PubMed, Wiley, Ovid-Medline y Science Direct. Los descriptores MESH utilizados para la búsqueda fueron cardiac myocytes, myocardium, heart conduction system. Se acoplaron los conceptos histology y arrhythmia. Se revisaron artículos publicados entre 1990 a 2014, originales, reportes de caso y revisiones, relacionados con los conceptos de desarrollo embrionario, diferenciación celular, morfología normal y alteración de los miocardiocitos conducentes ventriculares. Se revisó el resumen de 317 artículos, de los que se clasificaron 75 para lectura completa y de estos, 52 se seleccionaron para la redacción del presente artículo. Conclusión: Los estudios actuales se encaminan hacia las simulaciones del sistema de conducción para establecer otras causas de arritmia y opciones de tratamiento. La terapia con células indiferenciadas y las técnicas moleculares de modificación genética hacen parte de estos estudios, así como la implementación de terapias alternativas no invasivas en el tratamiento de las arritmias cardíacas.

Abstract

Objective: To expose the histological and functional characteristics that occur in heart striated muscle tissue specialized in the conduction of electrical stimulation and its current implications for cardiac arrhythmias. Materials and methods: Publications in indexed journals in PubMed, Wiley, Ovid-Medline and Science Direct databases were selected. The MESH descriptors used for the search were cardiac myocytes, myocardium and heart conduction system. The concepts of histology and arrhythmia were mated. Articles published from 1990 to 2014 were reviewed as well as the original ones, case reports and reviews related to the concepts of embryonic development, cell differentiation and normal morphology alteration of the leading ventricular cardiomyocytes. The summary of 317 articles were read, from which 75 were classified to complete reading and finally 52 were selected for the drafting of this article. Conclusion: Current studies are directed towards the driving system simulation to establish other causes of arrhythmia and its treatment options. Not only therapies with undifferentiated cells and molecular genetic modification techniques are part of these studies but also the implementation of alternative therapies that are not invasive in the treatment of cardiac arrhythmias.

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Biografía del autor/a

Doris Haydee Rosero Salazar, Universidad del Valle
Magíster en Ciencias Biomédicas, Profesora del Departamento de Ciencias Básicas de la Universidad Icesi. Profesora del Departamento
de Morfología Universidad del Valle. Cali, Colombia.
Mario Alejandro Ortiz Salazar, Universidad del Valle
Magíster en Ciencias Básicas Médicas, Profesor de Histología, Profesor Asistente. Investigador Grupo de Investigación Tejidos Blandos
y Mineralizados Universidad del Valle. Cali, Colombia
Liliana Salazar Monsalve, Universidad del Valle
Magíster en Morfología, Profesora Asociada, Coordinadora de Histología. Directora Grupo de Investigación Tejidos Blandos y
Mineralizados Universidad del Valle. Cali, Colombia.

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Publicado
2015-04-26
Cómo citar
Rosero Salazar, D., Ortiz Salazar, M., & Salazar Monsalve, L. (2015). Miocardiocitos conducentes ventriculares. Universidad Y Salud, 17(2), 262 - 270. https://doi.org/10.22267/rus.151702.10
Sección
Revisión de Tema