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Scientific and technological research article

Vol. 22 No. 1 (2020)

Functional gastrointestinal disorders in schoolchildren with chronic abdominal pain in a pediatric digestive endoscopy unit

DOI
https://doi.org/10.22267/rus.202201.174
Submitted
August 9, 2018
Published
2019-12-30

Abstract

Introduction: The indication of an upper digestive tract endoscopy (UDTE) in children with chronic abdominal pain (CAP) has little evidence. However, this test continues to be requested in children with functional gastrointestinal disorders (FGIDs). Objective: To determine the prevalence and possible associations of FGIDs in children of a Pediatric Digestive Endoscopy Unit using the Rome III Criteria. Materials and methods: A prevalence study of 37 schoolchildren. Sociodemographic, anthropometric and clinical variables were assessed. The statistical analysis included estimation of the proportion of children with FGIDs and its corresponding 95% CI. Other assessments included estimation of percentages, averages, standard deviations, ranges, univariate analysis, possible occurrence of associations between the variable, and a two-tailed Fisher's exact test with a significance set at p<0.05. Results: The mean age of child participants was 11.3±2.1 years and 62.2% of them were female. The prevalence of FGIDs was 73%, more than half of them presenting functional abdominal pain (FAP) and irritable bowel syndrome (IBS). There were no significant differences in terms of sociodemographic, anthropometric and clinical variables. Conclusions: The prevalence of FGIDs is high in children with CAP who undergo UDTE as part of the study of this disorder, being FAP and IBS the most frequent.

References

  1. Di Lorenzo C, Colletti RB, Lehmann HP, et al; AAP Subcommittee; NASPGHAN Committee on Chronic Abdominal Pain. Chronic abdominal pain in children: a technical report of the American Academy of Pediatrics and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. JPGN. 2005; 40(3): 249-61. https://journals.lww.com/jpgn/Fulltext/2005/03000/Chronic_Abdominal_Pain_In_Children__A_Technical.2.aspx
  2. Miele E, Giannetti E, Martinelli M, Tramontano A, Greco L, Staiano A. Impact of the Rome II pediatric criteria on the appropriateness of the upper and lower gastrointestinal endoscopy in children. Aliment Pharmacol Ther. 2010; 32(4): 582-90. doi: 10.1111/j.1365-2036.2010.04383.x.
  3. Bonilla S, Wang D, Saps M. The Prognostic Value of Obtaining a Negative Endoscopy in Children With Functional Gastrointestinal Disorders Clinical Pediatrics. 2011; 50(5): 396-401. doi: 10.1177/0009922810392773
  4. Campo JV, Comer DM, Jansen-Mcwilliams L, Gardner W, Kelleher KJ. Recurrent pain, emotional distress, and health service use in childhood. J Pediatr. 2002; 141(1): 76-83. doi: 10.1067/mpd.2002.125491
  5. Greco LA, Freeman KE, Dufton L. Overt and relational victimization among children with frequent abdominal pain: links to social skills, academic functioning, and health service use. J Pediatr Psychol. 2007; 32(3): 319-29. doi: 10.1093/jpepsy/jsl016
  6. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Childhood Functional Gastrointestinal Disorders: Child/Adolescent Gastroenterology. 2016; 150(6): 1456-68. doi: 10.1053/j.gastro.2016.02.015
  7. Rasquin A, Di Lorenzo C, Forbes D, et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2006; 130(5): 1527-37. doi: 10.1053/j.gastro.2005.08.063
  8. Saps M, Nichols-Vinueza DX, Rosen JM, Velasco-Benítez CA. Prevalence of Functional Gastrointestinal Disorders in Colombian School Children. J Pediatr. 2014; 164(3): 542-5. doi: 10.1016/j.jpeds.2013.10.088
  9. Zablah R, Velasco-Benítez CA, Merlos I, Bonilla S, Saps M. Prevalencia de trastornos funcionales gastrointestinales en niños en edad escolar en El Salvador. Rev Gastroenterol Mex. 2015; 80(3): 186-91. doi: 10.1016/j.rgmx.2015.03.008
  10. Lu PL, Saps M, Chanis RA, Velasco-Benítez CA. The prevalence of functionalgastrointestinal disorders in childrenin Panama: a school-based study. Acta Pædiatrica. 2016; 105(5): e232-6. doi: 10.1111/apa.13379
  11. Jativa E, Velasco-Benítez CA, Koppen IJN, Jativa-Cabezas Z,Saps M. Prevalence of Functional Gastrointestinal Disorders in Schoolchildren in Ecuador. JPGN 2016; 63(1): 25-8. doi: 10.1097/MPG.0000000000001108
  12. Mejía M, Velasco-Benítez CA, Díaz J. La prevalencia y las posibles asociaciones de los desórdenes gastrointestinales funcionales en escolares y adolescentes de colegios privados de Managua, Nicaragua. Acta Gastroenterol Latinoam. 2017; 47(3): 163-8. http://actagastro.org/la-prevalencia-y-las-posibles-asociaciones-de-los-desordenes-gastrointestinales-funcionales-en-escolares-y-adolescentes-de-colegios-privados-de-managua-nicaragua/
  13. Dhroove G, Saps M, Garcia-Bueno C, Jiménez AL, Rodriguez-Reynosa LL, Velasco-Benítez CA. Prevalencia de trastornos gastrointestinales funcionales en escolares mexicanos. Rev Gastroenterol Mex. 2017;82(1):13-8. doi: 10.1016/j.rgmx.2016.05.003.
  14. Saps M, Moreno-Gomez JE, Ramírez-Hernández CR, Rosen JM, Velasco-Benitez CA. A nationwide study on the prevalence of functional gastrointestinal disorders in school-children. Bol Med Hosp Infant Mex. 2017; 74(6): 407-12. doi: 10.24875/BMHIME.M17000012
  15. Saps M, Velasco-Benitez CA, Langshaw AH, Ramírez-Hernández CR. Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents: Comparison Between Rome III and Rome IV Criteria. J Pediatrics. 2018; 199: 212-6. doi: 10.1016/j.jpeds.2018.03.037
  16. Rouster A, Karpinski A, Silver D, Monagas J, Hyman P. Functional gastrointestinal disorders dominate pediatric gastroenterology outpatient practice. JPGN 2016; 62(6): 847-51. doi: 10.1097/MPG.0000000000001023
  17. Thakkar K, Chen L, Tessier ME, Gilger MA. Outcomes of Children After Esophagogastroduodenoscopy for Chronic Abdominal Pain. Clin Gastroenterol Hepatol. 2014; 12(6): 963-9. doi: 10.1016/j.cgh.2013.08.04
  18. Gupta S, Gupta G, Sharda P, Mittal K. Study evaluating chronic abdominal pain and functional abdominal pain syndrome. Int J Res Med Sci. 2015; 3(9): 2290-8. doi: 10.18203/2320-6012.ijrms2015061
  19. Di Lorenzo C. EGD for children with abdominal pain: the jury is still out. Nat Rev Gastroenterol Hepatol [Internet]. 2013;10(12):701–3. Available from: https://doi.org/10.1038/nrgastro.2013.214
  20. Gilger MA, Gold BD. Pediatric endoscopy: New information from the PEDS-CORI project. Curr Gastroenterol Rep [Internet]. 2005;7(3):234–9. Available from: https://doi.org/10.1007/s11894-005-0040-y
  21. Thakkar K, Gilger MA, Shulman RJ, El Serag HB. EGD in children with abdominal pain: a systematic review. Am J Gastroenterol [Internet]. 2007;102(3):654–61. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17222318
  22. Thakkar K, Chen L, Tatevian N, Shulman RJ, McDuffie A, Tsou M, et al. Diagnostic yield of oesophagogastroduodenoscopy in children with abdominal pain. Aliment Pharmacol Ther [Internet]. 2009;30(6):662–9. Available from: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2036.2009.04084.x
  23. Gómez MA, Ruiz OF, Riveros J. Diagnostic Usefulness of Upper Gastrointestinal Endoscopy for Patients under 18 Years of Age. Rev Col Gastroenterol. 2014; 29(2): 111-5. https://revistagastrocol.com/index.php/rcg/issue/view/20
  24. Wang S, Younus O, Rawat D, Naik S, Giles E, Meadows N, et al. Clinical Presentation and Outcomes of Diagnostic Endoscopy in Newly Presenting Children with Gastrointestinal Symptoms. J Pediatr Gastroenterol Nutr. 2018 Jun 1;66(6):876–81. DOI: 10.1097/MPG.0000000000001864
  26. Saps M, Seshadri R, Sztainberg M, Schaffer G, Marshall BM, Di Lorenzo C. A Prospective School-based Study of Abdominal Pain and Other Common Somatic Complaints in Children. J Pediatr. 2009; 154(3): 322-6. doi: 10.1016/j.jpeds.2008.09.047
  27. Gulewitsch MD, Enck P, Schwille-Kiuntke J, Weimer K, Schlarb AA. Rome III criteria in parents’ hands: pain-related functional gastrointestinal disorders in community children and associations with somatic complaints and mental health. Eur J Gastroenterol Hepatol [Internet]. 2013;25(10):1223-1229. Available from: https://doi.org/10.1097/MEG.0b013e328364b55d
  28. Zernikow B, Wager J, Hechler T, Hasan C, Rohr U, Dobe M, et al. Characteristics of highly impaired children with severe chronic pain: a 5-year retrospective study on 2249 pediatric pain patients. BMC Pediatr. 2012; 12: 54. doi: 10.1186/1471-2431-12-54
  29. Yacob D, Di Lorenzo C, Bridge JA, Rosenstein PF, Onorato M, Bravender T, et al. Prevalence of Pain-Predominant Functional Gastrointestinal Disorders and Somatic Symptoms in Patients with Anxiety or Depressive Disorders. J Pediatr [Internet]. 2013 Sep 1;163(3):767–70. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0022347613002400?via%3Dihub
  30. Devanarayana NM, Mettananda S, Liyanarachchi C, Nanayakkara N, Mendis N, Perera N, et al. Abdominal pain-predominant functional gastrointestinal diseases in children and adolescents: Prevalence, symptomatology, and association with emotional stress. J Pediatr Gastroenterol Nutr [Internet]. 2011;53(6):659–65. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21697745
  31. Boey CCM, Goh KL. The significance of life-events as contributing factors in childhood recurrent abdominal pain in an urban community in Malaysia. J Psychosom Res. 2001; 51(4): 559-62. doi: 10.1016/S0022-3999(01)00232-X
  32. van Tilburg MAL, Runyan DK, Zolotor AJ, Graham JC, Dubowitz H, Litrownik AJ, et al. Unexplained gastrointestinal symptoms after abuse in a prospective study of children at risk for abuse and neglect. Ann Fam Med [Internet]. 2010;8(2):134–40. Available from: https://pubmed.ncbi.nlm.nih.gov/20212300
  33. Iovino P, Tremolaterra F, Boccia G, Miele E, Ruju FM, Staiano A. Irritable bowel syndrome in childhood: visceral hypersensitivity and psychosocial aspects. Neurogastroenterol Motil. 2009 Sep;21(9):940-e74. doi: 10.1111/j.1365-2982.2009.01303.x
  34. Bonilla S, Saps M. Early life events predispose the onset of childhood functional gastrointestinal disorders. Rev Gastroenterol Mex. 2013 Apr-Jun;78(2):82-91. doi: 10.1016/j.rgmx.2013.02.001
  35. Tack J, Talley NJ. Functional dyspepsia—symptoms, definitions and validity of the Rome III criteria. Nat Rev Gastroenterol Hepatol [Internet]. 2013;10(3):134–41. Available from: https://doi.org/10.1038/nrgastro.2013.14
  36. Romano C, Valenti S, Cardile S, Benninga M. Functional dyspepsia: An enigma in a conundrum. JPGN 2016; 63(6): 579-84. doi: 10.1097/MPG.0000000000001344

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